The following is a list of characters in the Spawn universe.

Angels

• Anahita
• Angela
• Callindra
• Domina
• Gabrielle
• Grace - An angel guard (video games only)
• Heavenly Hosts
• Jinx
• Kuan Yin
• Melchidael - An angel mentioned in Angela Issue #1, where Surielle mentions that Angela was the only other Angel to be put in the maximum security cells since Melchidael was captured.
• Metatron
• Michaela
• Rafael
• Raphaela - An angel mentioned in Spawn issue #9 by Gabrielle. She was called "upstairs" and this allowed Gabrielle to take over as the Director of Terran Affairs.
• Saranyu
• Surielle
• Urania
• Tiffany
• Zera

Demons/Hellspawn

• %^2 †
• %^9 †
• Clown
• Hellspawn (Circa 1192)
• Smut
• Spawn
• The Prime
• Ticki-Tacki
• Vacillator
• Vandalizer
• Vaporizer
• Vindicator
• Violator

Humans

CIA Operatives

• Agent Roenick
• Al Simmons †
• Jason Wynn

Cops

• Agent Connors
• Bob
• Captain Burgess
• Charlie
• Louis Banks
• Sam Burke
• Twitch Williams
• Eric
• George
• Flynn
• Fred
• Jensen
• Lieutenant Troy
• Ramirez
• Smith

Creeps

• Buffy †
• James †

Cyborgs

• Byron †
• James †
• Overt-Kill

Homeless/Bums

• Bobbie
• Bobby
• Boots
• Charlie
• Dipper (Marty Sladek)
• E
• Emily
• Erik
• Freddy †
• Gareb
• Jack
• Jimmy D.
• Jimmy Linden
• Jody
• Joey †
• Louie
• Mr. Hughes
• Nicholas Cagliostro
• Paul
• Sherlock - A homeless man who lives in the Bowery's in New York City. He is only mentioned briefly in Spawn issue #9, and when the cops interrogated him about the Spawn sightings, his only response was a crude belch.
• Tricky Dick - A homeless man who lives alongside Spawn in the Bowery's of New York City, mentioned in Spawn issue #9. He along with some of the other homeless members of the alleyways were interrogated by cops who were looking for the "caped menace." After the cops give him a dollar, he says that he "has" seen the caped suspect...flying over the city every morning in a giant pink Cadillac with a big green gorilla.
• Vinnie
• Wilbur

Klansmen (KKK)

• Bill - A member of the KKK introduced in Spawn issue #30. He is one of the klansmen that carry off and linch Judge Zachery Missen, thinking that he was actually a black man.
• Gary - A member of the KKK introduced in Spawn issue #30. He is one of the klansmen that carry off and lynch Judge Zachery Missen, thinking that he was actually a black man.
• Jerry - A member of the KKK introduced in Spawn Issue #30. It is his barn that all the klansmen were supposed to meet at prior to driving out Brad Armstrong.
• Johnny
• Michael Balt
• Peter
• Ray Crabtree Jr.
• Zachery Missen

Mafia/KGB

• Alberto †
• Antonio Twistelli
• Bartino - A character who is mentioned by Anthony Twistelli in Spawn issue #6. He is apparently the owner of Overt-Kill and is assumed to be a Mafia Don who is based out of Italy.
• Carlo Giamotti †
• Frankie - A character who is mentioned by Anthony Twistelli in Spawn issue #24. He is mentioned to be sent back to Terry Fitzgerald's house to remove all evidence that the murdering of the two FBI Agents was actually the mob's doing.
• Gino †
• Gino (Restaurant Owner) - A character mentioned by Anthony Twistelli in Spawn issue #24. He is heard making a disturbing phonecall to Tony Twist, stating that there will be a meeting to discuss the handling of the current situation that the mob is dealing with.
• Jake †
• Jake Morelli - A mob boss who was considered almost 'untouchable' in 1992. He is mentioned only in issue #1 of Spawn on 2 Today.
• Joe Sakic †
• Larry (Goon) †
• Louie (Goon)
• Misha
• Smithers
• Tommy (Goon 1) †
• Tommy (Goon 2) †
• Tommy (Goon 3) - A character who is mentioned by Anthony Twistelli in Spawn issue #24. He is mentioned to be sent back to Terry Fitzgerald's house to remove all evidence that the murdering of the two FBI Agents was actually the mob's doing.
• Tony

Military

• Commander Cooper - A commander in the United States Army who is first introduced in Spawn #36. He is piloting one of the choppers that destroys the roof of the Merrill Lynch Building.
• Johnson
• Larry Brewer †
• Major Vale †
• Private Marty Sladek
• Sergeant Ico †
• Stevens †
• Taylor - One of the military guards who chase after Spawn in Spawn issue #36, when Jason Wynn is attacked.

Nerds

• Boomer †
• Byron †
• Norton †

Phlebiac Brothers

• Vacillator
• Vandalizer
• Vaporizer
• Vindicator
• Violator

Punks

• Bernie
• Brains †
• Clint
• Divvy †
• Doug "Mad Dog" Gilmour
• Joey
• Link †
• Mark
• Mr. Stewart
• Shank †
• Smokey †
• Spaz

Youngblood Operatives

• Badrock
• Chapel
• Diehard
• Giger
• Riptide
• Shaft

Villains

• Anti-Spawn
• Billy Kincaid (Mr. Chill-ee) †
• Chapel
• Clown
• John Sansker
• Malebolgia
• Overt-Kill
• The Admonisher
• The Curse
• Redeemer
• Satan
• Tremor
• Vacillator
• Vandalizer
• Vaporizer
• Vindicator
• Violator

Miscellaneous

• Amanda Jennings †
• Andrei Zlenko
• Andrew Horne
• Andy †
• Andy Frank
• Anne Thomopoulos
• Beth Vaisanen - An Alabama girl who is only mentioned briefly in Spawn issue #29. Eddie is telling Andy the he heard she had a crush on him.
• Billy †
• Billy Miller
• Bob †
• Brad Armstrong
• Cerebus
• Chris Albrecht
• Claudette †
• Connie - An acquaintance of Wanda who is introduced in Spawn #23. She is the one who calls Wanda at Grandma Blake home to tell her that two men were shot and killed on her lawn (courtesy of the mob).
• Cyan
• David - One of the children who was murdered by Billy Kincaid back in 1986.
• David Brewi
• Don
• Dr. John Dee †
• Dr. Reynolds - One of the doctors whom is helping with the diagnosis of Billy Kincaid. He agrees that after time spent, Billy Kincaid is ready to go back out into the world.
• Eddie Frank
• Erik
• Foo-Foo - A dog who's name is only mentioned once in Spawn issue #13. It was apparently almost a victim of a freak chainsaw massacre. Sam Burke is the detective who is filing the complaint when Foo-Foo's owner comes into the 12th Precinct.
• Fred Barnett †
• Gallagher - A vampire who lived in Poland sometime after World War I. First mentioned in Spawn Blood Feud issue #4, it is revealed that he was killed by John Sansker.
• Gottfriedsun - A monster who lived in Sweden. First mentioned in Spawn Blood Feud issue #3, he took three silver bullets to the brain before dying.
• Grandma Blake
• Gregor †
• Harry †
• Jacob 'Sonny' Groenfeld
• Jean Perry
• Jeff Pittman
• Jerry †
• Jessica †
• Joe Frank †
• Johnny - An acquaintance of Louie"s and makes his drunken mention in Spawn issue #5. In the alleyways of New York City, Louie is seen telling some others about a time when Johnny called him the "Destructor of Society."
• Julia
• Karen Horne
• Katie Barnett
• Kimberly †
• Larry (White) †
• Larry (Black) †
• Leroy †
• Linda
• Mabel - Bobby's aunt, who was briefly mentioned in issue #7 of Spawn.
• Mark Curtis - An author mentioned by the news-anchor of Entertainment Television in Spawn issue #12. It is revealed that this is the author of the best-selling biography "Courageous Ambitions: The Al Simmons Story", and has just sold the movie rights to Paramount Pictures.
• Marla Fleet - A character mentioned in issue #5. A former Miss Universe winner, Marla Fleet got a lot of media attention after having a public affair with Senator Paul Jennings.
• Martin Alexander - A character mentioned in Spawn issue #1 by the news anchor from Channel 7 News. He was Wanda Blake's best friend in High School and was the one who introduced Al Simmons to her at the Republican Convention in 1984.
• Maryanne - An acquaintance of Wanda's who is first mentioned in Spawn issue #21. It is stated that she will be heading over to watch Cyan while Wanda and Terry head out on a dinner date.
• Mike - A character mentioned in Spawn issue #10. When Spawn is being shown around the alternate realm by Cerebus, he calls Al Simmons' home phone. He is seen to want to meet up with Cerebus after the Leaf game.
• Mr. Nunoz - The owner of a restaurant in New York City. His name is only mentioned once in Spawn issue #15, but it is revealed that it is a 'hot-spot' for the homeless to raid in search of food scraps. The alleyway behind the restaurant is the setting for one of Spawn's "non-power using" battles with an angry brute.
• Pam Palmer
• Senator Paul Jennings
• Percival Issacsen-Smythe - A friend of Terry Fitzgerald's who is first mentioned in Spawn issue #20. After being beaten by Yousef's goons, he calls Percy to help him by sending him backup.
• Peter - One of the children who was murdered by Billy Kincaid back in 1986.
• Phil †
• Phil Timper
• Pierre
• Porsche MacNeil
• Rob
• Roy Peck - The Detroit werewolf. First mentioned in Spawn Blood Feud issue #4, it is revealed that he was killed by John Sansker.
• Sabrina Cambridge - A monster of some sort. First mentioned in Spawn Blood Feud issue #4, it is revealed that she was killed by John Sansker.
• Shanna
• Sheila Egger - An acquaintance of Wanda and Terry and is first mentioned in Spawn issue #28. Wanda had told Terry that she was going to Sheila's place to discuss a new charity.
• Sherlee Johnson †
• Sonny †
• Stuart - One of the children who was murdered by Billy Kincaid back in 1986.
• Suzy - One of the children who was murdered by Billy Kincaid back in 1986.
• Terence D. Fitzgerald
• Terri - One of the children who was murdered by Billy Kincaid back in 1986.
• Tommy †
• Ursula Meyer - Mentioned in Spawn Blood Feud issue #3, she was a Lamia who lived in Frankfurt, Germany. She was decapitated, however her body kept fighting for ten minutes.
• Van Zandt - A vampire from Los Angeles who is first mentioned in Spawn Blood Feud issue #4. Not much is revealed about him, aside from the fact that he was one of the brightest and best vampires, and was killed by sucking the blood of someone with AIDS.
• Wanda Blake
• Yousef Volokhov